Probiotics Prevents Hirschsprung's Disease Associated Entercolitis: A Prospective Multicenter R

来源 :中华医学会小儿外科学分会全国小儿外科学术研讨会 | 被引量 : 0次 | 上传用户:doodoo
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Objective We conducted a prospective,multicenter,randomized and controlled trial to assess whether oral probiotics could decrease the incidence and severity of HAEC.Methods HD patients were randomly assigned into the control group and probiotics-treated group.All children in probiotics-treated group were fed with probiotics per day for 4 weeks.Results The incidence and severity of EC was also remarkably decreased.Furthermore,probiotics balanced T lymphocytes subsets.Conclusions Probiotics not only significantly diminished the incidence,but also decreased the severity of HAEC.Moreover,our study revealed that probiotics decreased pro-inflammatory cytokine and increased anti-inflammatory cytokine and furthermore balanced T Lymphocytes.
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