Ma Reversal of Diabetes Development through Balancing the Ratios of ω-6ω-3 PUFAs

来源 :2014 International Symposium on Polyunsaturated Fatty Acids | 被引量 : 0次 | 上传用户:metoo321
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Cardiova Colorectal can A series of epidemiological studies have established the health benefits of dietary intake of ω-3 PUFAs in preventing cardiovascular diseases and diabetes.Two recent large-scale clinical studies also demonstrated that long-term dietary intake of fish oil starting at 1 year of age lowers the risk of type 1 diabetes and islet autoimmunity.Using nutritional intervention and a genetic transgenic model fat-1 capable of endogenously producing ω-3 PUFAs, we have recently established that balancing the ω-6/ω-3 PUFAs can confer resistance to high-fat diet induced obesity, diabetes, dyslipidemia, hepatic steatosis, and inflammation.
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