Genetic Polymorphisms in Cyclooxygenase-2 are Associated with Radiotherapy Response and Survival in

来源 :中国抗癌协会肿瘤放射治疗专业委员会学术大会、中美放射肿瘤协会第三届学术会议、2012济南国际放射肿瘤学论坛 | 被引量 : 0次 | 上传用户:jhiphop
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Purpose:COX-2 plays important roles in modulation of immune response,apoptosis,angiogenesis,and tumor invasion.COX-2 expression was reported to correlate with survival after radiotherapy and the response to radiotherapy.This study investigated whether genetic variations in COX-2 gene are associated with radiotherapy response and the survival in esophageal squamous cell carcinoma(ESCC)patients treated with preoperative radiotherapy.
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