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A simple dual sensing of CN-and Ag+ was first time reported by naphthalene based lab-on-a-molecule containing benzothiazole in DMF buffered aqueous solution.With CN-and Ag+,probe 1 showed highly selective and sensitive responses towards CN-and Ag+ in both UV-Vis and fluorescence channels over other tested ions.Meanwhile,the 10 sensing mechanism of both title ions was further studied by NMR titration and XPS experiments.