A novel PADI4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute prom

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：wk8954642

【摘要】

：

　　Aims: The hematologic malignancy acute promyelocytic leukemia (APL) exhibits a failure of myeloid differentiation.Most patients with APL can be induced to c

【作者】

：

GuanhuaSong;LuluShi;YuqiGuo;LinchangYu;LinWang;XiaoyuZhang;LianlianLi;XiaRen;QiangGuo;GuoshengJiang;

【机构】

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Institute of Basic Medicine,Shandong Academy of Medical Sciences

【出处】

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中国免疫学会第十届全国免疫学学术大会

【发表日期】

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2015年期

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　　Aims: The hematologic malignancy acute promyelocytic leukemia (APL) exhibits a failure of myeloid differentiation.Most patients with APL can be induced to complete remission by all-trans retinoic acid (ATRA) or arsenic trioxide treatment through presumed degradation of the PML-RARα fusion protein.

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A novel PADI4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute prom

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