Construction and protective efficacy of recombinant clod-adapt influenza vaccine strain as a vector

• 作 者: MengyingCai[1]sujingSun[1]HongjingGu[1]YueqiangDuan[1]ChengcaiLai[1]LiXing[1]PenghuiYang[2]XiliangWang[1]
• 机 构: Beijing Institute of Microbiology and Epidemiology
• 出 处: 中国免疫学会第十届全国免疫学学术大会
• 发表日期: 2015年期

　　In this sdudy we use attenuated cold-adapted influenza vaccine strains as a platform to express fitted RSV F protein and antibody epitopes.And intranasally immunized 6-8 week female BALB/c mice to evaluate the immunogenicity and protective effacy of the candidate vaccine.