The Age of Big Data Big gap between the dramatically increased biological data and our abilities of computation,data mining,and knowledge discovery
Why study proteomics Proteins are the workhorses of the cell-enzymes,structural proteins,signal transduction,transcription,translation and degradation,transport
Outline Background Data source Analyze workflow Result interpretation Database construction Genome visualization tool Summary Perspective
Different users for different needsSome users need detailed knowledge on a protein in free text
RefSeq overview What is RefSeq?How does it compare to GenBank?What are the advantages?How is the dataset built?
Life Is Tempo-spatial … Cell is 3-D… The New Paradigm:(Genetics+Epigenetics)+Genes are aligned linearly on DNA but organized in multi-dimensions as chromosome
Genomes:The good,the bad and the ugly The story(dated to Civil War 1862) traces how 3 men gain information about the location of a buried treasure of gold,and t
GenBank GenBank is a primary nucleotide sequence archive containing all public assembled and annotated sequences submitted as part of the publication process.