microRNAs in the same clusters evolve to coordinately regulate functionally related genes

来源 :2016年第三届全国功能基因组学学术峰会 | 被引量 : 0次 | 上传用户:yanlingyanling
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MicroRNAs (miRNAs) are endogenously expressed small non-coding RNAs.The genomic locations of animal miRNAs are significantly clustered in discrete loci.We found duplication and de novo formation were important mechanisms to create miRNA clusters and the clustered miRNAs tend to be evolutionarily conserved.
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