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Background The current overweight and central adiposity guidelines based on Western populations were not consistent with many studied based on the Asian populations.Uighur people live in Xinjiang Uighur Autonomous Region which is located in the center of Asia.Their overweight and central cutoffs were largely unknown.We aimed to identify cutoffs for body mass index (BMI;in kg/m2) and waist circumference (WC;in cm) for categorization of overweight and central adiposity among Uighur adults in Xinjiang.