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  5. Strategies to improve Asulacrine retention within liposomes with DPPG and loading by glutathione gra

Strategies to improve Asulacrine retention within liposomes with DPPG and loading by glutathione gra

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：ayong790401
【摘 要】
：
Many anticancer drugs like Asulacrine (ASL) could cause severe phlebitis in patients after intravenous infusion.Liposomes were found to prevent these side effects and offer tumor-targeted drug deliver
【作 者】
：
Wenli Zhang Bruce C.Baguley John P.Shaw Caibin Li Jianping Liu Zimei Wu 
【机 构】
：
School of Pharmacy,The University of Auckland,Auckland,1142,New Zealand;China Pharmaceutical Univers
【出 处】
：
Fourth Symposium on Innovative Polymers for Controlled Deliv
【发表日期】
：
2016年11期
【关键词】
：
negative-charged phospholipid liposomal drug retention glutathione cyclodextrin 
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　　Many anticancer drugs like Asulacrine (ASL) could cause severe phlebitis in patients after intravenous infusion.Liposomes were found to prevent these side effects and offer tumor-targeted drug delivery.However,there are many literature reports of drug leakage from liposomes[1].
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