Macrophage-activating lipopeptide-2 requires Mal and PI3K for efficient induction of hemeoxygenase-1

• 作 者: XiaoxingYou[1]XiaohuaMa[2]YanhuaZeng[1]CuimingZhu[1]LiesongChen[1]JunHe[3]ZhongliangDeng[1]ChuanhaoJiang[1]MinjunYu[1]YimouWu;
• 机 构: Institution of Pathogenic Biology, Medical College, University of South China, Hengyang, China, 4210
• 出 处: The 6th Meeting of the Asian Organization for Mycoplasmology
• 发表日期: 2014年期

　　Exposure to Mycoplasma leads to genitourinary tract or lung inflammation through a host defense pathways.Increasing evidence have indicated that the mycoplasma derived membrane lipoproteins, or its analogue macrophage-activating lipopeptide-2 (MALP-2), exert as LPS as an immune system-stimulating substance and play a crucial role in the pathological Injury during mycoplasma infection.