【摘 要】
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Objective: Bisphosphonates (BP) are antiresorptive drugs that block osteoclast recruitment, decrease osteoclast activity and promote osteoclast apoptosis.They are used in the treatment of patients wit
【机 构】
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Dept.of Oral and Maxillofacial Surgery,School of Dentistry,Pusan National University,Korea
【出 处】
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11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲
论文部分内容阅读
Objective: Bisphosphonates (BP) are antiresorptive drugs that block osteoclast recruitment, decrease osteoclast activity and promote osteoclast apoptosis.They are used in the treatment of patients with osteoporosis, in cancer patients such as multiple myeloma, carcinomas of prostate and breast with bone metastasis.A well-recognized side effect of BP therapy is BP-related osteonecrosis of the jaws (BRONJ), first described by Marx in 2003.The purpose of this study was to identify factors that influence BRONJ.
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