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Objectives: Dentin hypersensitivity has been a kind of common symptom characterized as a brief,sharp pain.Many topically applied materials and treatments can produce promising yet relatively short-lived therapeutic effects.Recently,dentin desensitizing agents containing bioactive glass have been shown to have potential clinical efficacies.The aim of this study was to compare the long-term in vitro effectiveness of a desensitizing agent containing bioactive glass and two other commercial products employed for dentin hypersensitivity.