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Adopt the mixed solution of crude oil which was from the Xingbei development Polymer flooded zone of Daqing oilfield and oil injection water.The Behavior of polymers-crude mixture solution pipeline flow is researched by the vertical shaft pipe flow experimental device in laboratory.The Flow rules of solution flowed in vertical pipe and the annular space is obtained.Dependent the flow rules and rheological properties of Polymer flooding pumping Wells produced liquid in the tubing wellbore,the mathematical model of friction calculation that used to Polymer flooding pumping Wells produced liquid that was from Xingbei development zone is established.