Downregulation of Imprinted Gene ARHI Could Contribute to Human Hepatocinogenesis

来源 :2007年生物芯片与疾病分子分型国际研讨会(International Symposium on Biochip Tec | 被引量 : 0次 | 上传用户：wei2006006

【摘要】

：

　　Identification of cancer genes differentially expressed in hepatocellular carcinoma (HCC) will play important role in understanding the molecular mechanisms

【作者】

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Jian Huang Yun Lin Xiao-Mei Teng Yun-Li Zhang Ze-guang Han

【机构】

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Shanghai-MinistryKeyLaboratoryofDiseaseandHealthGenomics,ChineseNationalHumanGenomeCenteratShanghai,

【出处】

：

2007年生物芯片与疾病分子分型国际研讨会(International Symposium on Biochip Tec

【发表日期】

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2007年5期

【关键词】

：

ARHI Hepatocellular carcinoma hypermethylation cell proliferation RNA interferen

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　　Identification of cancer genes differentially expressed in hepatocellular carcinoma (HCC) will play important role in understanding the molecular mechanisms of hepatocarcinogenesis.Here,we investigated expression of ARHI through RT-PCR and found ARHI was significantly down-regulated in 38 of 73 (52%) HCC specimens compared to adjacent non-cancerous livers.

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