Physalin B reduce secretion of Aβ by inhibiting phosphorylation ofSTAT3 via down-regulated expressio

来源 :2019全国老年痴呆与认知障碍相关疾病学术大会 | 被引量 : 0次 | 上传用户：sjtygk

【摘要】

：

OBJECTIVE Extracellular amyloid-β(Aβ)plaques are one of the major pathological hallmarks of Alzheim-er disease(AD).Therefore,decreasing Aβ levels is one strategyfor preventing the etiology of AD.

【作者】

：

BAI Shan-shan ZHUO Lin SUN Yi SHI Ru-ling XIE Yong-sheng ZHANG Wei

【机构】

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School of Basic Medical Sciences,Xinxiang Medical University,Xinxiang 453003,China

【出处】

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2019全国老年痴呆与认知障碍相关疾病学术大会

【发表日期】

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2019年10期

【关键词】

：

Alzheimer disease Physalin B β-amyloid protein BACE1 PS1 STAT3

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　　OBJECTIVE Extracellular amyloid-β(Aβ)plaques are one of the major pathological hallmarks of Alzheim-er disease(AD).Therefore,decreasing Aβ levels is one strategyfor preventing the etiology of AD.

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Physalin B reduce secretion of Aβ by inhibiting phosphorylation ofSTAT3 via down-regulated expressio

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