钩吻素子对Ⅱ型胶原诱导关节炎大鼠T辅助细胞亚群的调节作用

来源 :第十七届全国神经精神药理学学术会议 | 被引量 : 0次 | 上传用户：my561

【摘要】

：

目的观察钩吻素子对Ⅱ型胶原诱导关节炎大鼠T 辅助细胞亚群的调节作用.方法选用雄性Wistar 大鼠建立Ⅱ型胶原诱导关节炎(CIA)模型，大鼠分为对照组、模型组、甲氨蝶呤(1 mg·kg-1)组和钩吻素子(0.6 和15 mg·kg-1)处理组，每组10 只.初次免疫后第21 天开始灌胃给药，每天1 次，连续10 d.

【作者】

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杨渐陈泽鸿方梦寒俞昌喜

【机构】

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福建医科大学药学院药理学系,福建福州350108

【出处】

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第十七届全国神经精神药理学学术会议

【发表日期】

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2016年5期

【关键词】

：

钩吻素子类风湿关节炎 T辅助细胞极化偏移

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钩吻素子对Ⅱ型胶原诱导关节炎大鼠T辅助细胞亚群的调节作用

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