As a new drug delivery system,nanomedicine has a broad market prospect.It remains a major challenge to advance clinical translation of nanomedicine due to i
Because of the unparalleled efficiency and universal utility in treating theoratically all disease types,siRNA agents have evolved as the future drug-of-cho
Recently,our research group discovered the novel use of a series of near-infrared fluorescent(NIF)probes with parent structures of 4,4′-difluoro-4-bora-3a,
Disruption of mitochondrial Ca2+homeostasis has been reported as an effective antitumor strategy,while how to contribute to mitochondrial Ca2+overload effec
Due to independence on tumor type and excellent applicability,hyperpyrexia-mediated tumor ablation is focus in scientific community including material scien
This study aimed to construct a system consisted by paclitaxel(PTX)and temozolomide(TMZ)co-loaded mPEGDPPE calcium phosphate nanoparticles(NPs)and injectabl
The nanodrug carrier technology plays an important role in solving the impediment of druggability.The carrier druggability is essential in designing drug de
The artificial “Chassis” functioned as framework of virus,to stabilize antigen and increase the immune-response of antigen.We have developed a membrane em
Intestinal mucosal barrier includes intestinal epithelium barrier and mucus barrier.The intestinal epithelium is a cell layer that connected by tight juncti
The tumor vasculature is an attractive target for tumor therapy.It has been reported that when tumors grow to a size larger than 2-3 mm3,their continued gro