One-step gene delivery into cytoplasm in a fusion-dependent manner based on a new membrane fusogenic

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：emydisk

【摘要】

：

In the past two decades,gene therapy has shown promising potential to treat a variety of diseases,such as cancer,viral infection and cardiovascular diseases[1].However,due to the rapid degradation in

【作者】

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Hongzhang Deng Anjie Dong

【机构】

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Department of Polymer Science and Technology and Key Laboratory of Systems Bioengineering of the Min

【出处】

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Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

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2016年11期

【关键词】

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gene delivery fusion-dependent lipid one-step

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　　In the past two decades,gene therapy has shown promising potential to treat a variety of diseases,such as cancer,viral infection and cardiovascular diseases[1].However,due to the rapid degradation in systemic circulation and poor cellular internalization efficiency of gene,appropriate non-viral vectors for gene delivery were necessary to realize its full therapeutic potential.

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One-step gene delivery into cytoplasm in a fusion-dependent manner based on a new membrane fusogenic

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