【摘 要】
：
The age of parenthood has been steadily increased during the last decades, so it is very important to study the influence of aging on reproductive outcomes.The adverse effect of female aging has been
【机 构】
：
Department of Reproductive Medicine, the Third Affiliated Hospital of Guangzhou Medical University,G
【出 处】
：
广东省医学会第五次生殖医学学术会议
论文部分内容阅读
The age of parenthood has been steadily increased during the last decades, so it is very important to study the influence of aging on reproductive outcomes.The adverse effect of female aging has been widely investigated.In contrast, the impact of advanced paternal age has been comparatively less studied and there was no consensus on its role in reproduction.In our study weinvestigate the effect of male age on the reproductive outcomes of in vitro fertilization (IVF).We retrospectively analyzedthe data of IVF cycles in the Reproductive Medicine Center of the Third Affiliated Hospital of Guangzhou Medical Universitybetween January 2007 and October 2013.The samples were divided into three groups according to female age(<30, 30-34,35-38)and each group was subdivided into six groups according to the male age(<30, 30-32, 33-35,36-38, 39-41, ≥42).The main outcomes were embryo quality, fertilization rate, implantation rate, pregnancy rate, miscarriage rate.There were totally 9991 cycles included in this study.Female age was <30 years in 3327 cycles, 30-34 years in 4587 cycles and 35-38 years in 2077 cycles.There was no statistical significance when considering the fertilization rate, number of useful embryos, number of high-quality embryos and miscarriage rate (P >0.05).Chi-squared analysis revealed no statistical difference regarding implantation rate and pregnancy rate in different male age groups when female age was <30 and 35-38 years (P >0.05).However, implantation rate and pregnancy rate significantly decreased with male age when woman was 31-34 years (P <0.05).Our study concluded that male age had no impact on fertilization rate, embryo quality of cleavage stage and miscarriage rate but negatively affected implantation rate and pregnancy rate when woman was 31-34 years.
其他文献
目的 通过舒巴坦或舒巴坦复合制剂与其他药物的体外联合药敏实验,探讨联合用药对泛耐药鲍曼不动杆菌菌株的体外抗菌活性,从而为临床联合用药治疗泛耐药鲍曼不动杆菌感染提供药敏依据.方法 收集南方医院2012年2月份至12月份间临床分离的泛耐药鲍曼不动杆菌菌株50株,通过体外联合药敏实验,探讨联合用药对这些泛耐药鲍曼不动杆菌菌株的抗菌效应.结果 舒巴坦单用时MIC主要分布在32μg/ml与64μg/ml两个
目的 强直性脊柱炎(AS)是与HLA-B27相关的风湿性疾病.症状出现于16岁以前者定义为幼年起病强直性脊柱炎(JAS),占AS的10％-20％.JAS在多方面与成人起病AS(AAS)不同,本研究比较携带不同B27亚型的JAS患者临床特征,及分析JAS和AAS患者临床表现的差异.方法 2005-2013年间就诊于我院的JAS组患者145例,AAS组患者360例.回顾性分析患者病史、体检、强直性脊柱
目的 通过广州地区多中心临床研究评价GZ-2002急性淋巴细胞白血病(ALL)方案治疗儿童非高危ALL的长期疗效及预后.方法 总共7家单位统一采用GZ-2002-ALL化疗方案,对2002年10月至2008年6月收治的初诊非高危ALL患儿进行诊疗,并随访至2014年7月31日.运用Kaplan-Meier生存曲线及Log-Rank卡方检验研究患儿的生存情况、疗效及预后.结果 共433名0-16岁的
目的 分析中山地区过敏性疾病儿童的家居环境中尘螨变应原的曝露情况，为本地区儿童过敏性疾病的防治提供科学依据。方法 选择2014年7月～10月在中山市博爱医院儿科门诊被诊断为尘螨过敏性哮喘和/或鼻炎的儿童患者，由经过专门培训的工作人员应用真空吸尘器按统一吸尘方法上门收集儿童患者家中卧室的床尘，吸尘滤盘放入冰箱-20℃保存直至需要运送到实验室。分别测定家居尘样的中屋尘螨(Der p1)和粉尘螨(Der
Purpose: to describe and classify the MRI features of the brainstem encephalitis induced by EV71 based on three phases.Material and method: Neuroimaging data of 60 Pre and post contrast MRI studies in
疾病观察:糖尿病并发症风险需尽早干预,全程控制深入探讨:糖尿病并发症病理途径探讨临床观点:糖尿病并发症治疗的核心策略糖尿病并发症风险因素众多糖尿病并发症有着众多风险因素,包括年龄1家族或既往病史1高血压1血脂紊乱1胰岛素使用2β细胞功能下降3
目录起始胰岛素治疗的时机与方案的选择预混人胰岛素vs预混胰岛素类似物简约强化低预混直接转换为中预混病例1:口服降糖药失效的胰岛素起始治疗
目录01 流病糖尿病患者中下肢动脉病变高发02 危害下肢动脉病变的危害主要有两方面03 筛查与诊断提倡早期筛查和诊断下肢动脉病变04 治疗凯那是治疗下肢动脉病变的基础用药中国是糖尿病高发国家近30年,我国糖尿病患病率显著增加上述调查的方法和诊断标准并不一致糖尿病患者中下肢动脉病变高发入选664例住院2型糖尿病患者,共247人符合下肢动脉病变诊断标准
目的 观察体外条件下抗着丝粒抗体(anti-centromere antibody,ACA)是否进入活的早期胚胎内,及其对早期胚胎发育的可能影响。方法 将多克隆抗着丝粒蛋白-A(CENP-A)抗体与小鼠早期胚胎体外共培养,免疫荧光检测胚胎内是否出现定位于细胞核的抗体信号,并观察胚胎的发育能力是否受损。结果 体外与抗CENP-A抗体共培养的所有小鼠早期胚胎的细胞核内均检测到抗体荧光信号,对照组的所有
Background: Aneuploidy is a leading cause of repeat implantation failure and recurrent miscarriages.Preimplantation genetic screening (PGS) enables the assessment of the numeric chromosomal constituti