【摘 要】
：
Balancing treatment allocation for influential covariates is critical in clinical trials.This becomes increasingly important, as more and more biomarkers ar
【机 构】
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University of Virginia Department of Statistics Charlottesville, VA 23059, USA
【出 处】
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The Third IMS-China International Conference on Statistics a
论文部分内容阅读
Balancing treatment allocation for influential covariates is critical in clinical trials.This becomes increasingly important, as more and more biomarkers are found to be associated with different diseases in translational research (genomics, proteomics, and metabolomics).Stratified permuted block randomization and the covariat-adaptive designs (Pocock and Simon, 1975, etc.) are the two most popular approaches in practice.
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