【摘 要】
：
Extensive studies reveal that cancer genomes are frequently altered in their chromosomal structure by insertion, deletion, translocation and inversion of DN
【机 构】
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中国科学院北京生命科学研究院,北京100101
【出 处】
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中国遗传学会第九次全国会员代表大会暨学术研讨会
论文部分内容阅读
Extensive studies reveal that cancer genomes are frequently altered in their chromosomal structure by insertion, deletion, translocation and inversion of DNA fragments.Such alterations (termed as structural variation, SV) may produce various phenotypic effects in tumorigenesis and various human genetic disorders.However, current SV detection algorithms are far from being perfect and have limits in terms of the type and size of SVs that they are able to detect.
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