Cigarette Smoke Extract (CSE) Induces Transient Receptor Potential Ankyrin 1 (TRPA1) Expression via

• 作 者: Yichu Nie Chuqin Huang Shan Zhong Michael A.Wortley Yulong Luo Wei Luo Yanqing Xie Kefang Lai Nanshan Zhong
• 机 构: State Key Laboratory of Respiratory Diseases, the First Affiliated Hospital of Guangzhou Medical Uni
• 出 处: 第二届国际咳嗽会议(2nd International Cough Conference)
• 发表日期: 2015年10期

　　We previously found that transient receptor potential ankyrin 1 (TRPA1) in guinea pig tracheal epithelial cells was elevated after 14 days of cigarette smoke (CS) exposure.However,the mechanism underlying CS-induced TRPA 1 expression remains unknown.Here,we explored whether cigarette smoke extract (CSE)-induced TRPA1 expression is related with modulation of HIF1α in A549 cells.