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Due to plants of the Dipterocarpaceae family living in the tropical regions with strong UV light, and plant diseases and insect pests, the long-term evolution makes them produce resveratrol oligomers with structural diversity and remarkable bioactivities to cope with the challenges, which are increasingly becoming an important source for natural products research.Moreover, plant endophytic fungi living in special habitats and possessing the high mutation probability have been proven to be a new source of bioactive substances with novel skeleton.To deal with many diseases threatening human being, the two biological materials have attracted more and more attention in order to find new lead compounds for drug discovery.