Protective Roles of Hepatic GABAergic Signaling in Ethanol-induced Liver Injury

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:haozhizhegogo
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  Background: Gamma-aminobutyric acid(GABA)is produced by various cells through the catalytic activity of glutamic acid decarboxylase(GAD).We recently found that hepatocytes were endowed with type-A GABA receptor(GABAAR)mediated signaling mechanism,which protected the liver against toxic injury in rats.In neurons GABAARs are one of the major targets for alcohol.
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