【摘 要】
：
目的 探讨监测WT1基因对急性髓系白血病(AML)及骨髓增生异常综合征(MDS)患儿进行异基因造血干细胞移植(allo-HSCT)后的临床意义.方法 本文回顾性分析了2009年1月至2012年12月在我单位行allo-HSCT、且移植后连续监测WT1基因至少1年的36例儿童AML/MDS患者.留取移植后+30、+60、+90、+180、+270、+360天、+18月、+24月、+30月、+36月骨
【机 构】
：
北京大学人民医院,北京大学血液病研究所,造血干细胞移植治疗血液病北京市重点实验室 100044
【出 处】
：
中华医学会血液学分会第九次全国造血干细胞移植学术会议
论文部分内容阅读
目的 探讨监测WT1基因对急性髓系白血病(AML)及骨髓增生异常综合征(MDS)患儿进行异基因造血干细胞移植(allo-HSCT)后的临床意义.方法 本文回顾性分析了2009年1月至2012年12月在我单位行allo-HSCT、且移植后连续监测WT1基因至少1年的36例儿童AML/MDS患者.留取移植后+30、+60、+90、+180、+270、+360天、+18月、+24月、+30月、+36月骨髓标本,采用实时定量聚合酶链反应(RQ-PCR)的方法检测WT1基因表达水平,同时行流式细胞学(FCM)检测白血病残留.
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