【摘 要】
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The multidrug resistance 1 (MDR1) gene product P-glycoprotein is an ATP-dependent efflux pump associated with chemotherapy failure in breast cancer.In the present study,we show that paclitaxel induces
【机 构】
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MOE Key Laboratory of Model Animals for Disease Study,Model Animal Research Center and the School of
【出 处】
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中国细胞生物学学会2013年全国学术大会
论文部分内容阅读
The multidrug resistance 1 (MDR1) gene product P-glycoprotein is an ATP-dependent efflux pump associated with chemotherapy failure in breast cancer.In the present study,we show that paclitaxel induces MDR1 expression in the MCF-7 breast cancer cell line in a MAPK/Egr-1-dependent manner.
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