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目的利用腮腺显像研究甲状腺癌术后患者接受放射性碘(131I)治疗后腮腺的摄取与排泄功能。方法 32例甲状腺癌术后患者分为首次治疗组(组1)20例,重复治疗组(组2)12例,全部接受131I治疗前及治疗后3个月进行腮腺显像,分别计算腮腺的放射性摄取指数(UI)及酸性刺激后排泄指数(EI),并对腮腺功能损伤情况进行分析。结果甲状腺癌术后患者首次治疗组131I治疗后3个月腮腺UI和EI分别下降24.7%和25.5%(t值分别为2.0265,2.1043,P值分别为0.0498,0.0420);重复治疗组131 I治疗后腮腺UI和EI分别下降34.4%和39.7%(t值分别为1.1204,2.1575,P值分别为0.0455,0.0422);但两组间治疗后腮腺UI和EI比较差异无统计学意义(治疗后t’(UI)=1.2331治疗后t’(EI)=1.0474 P值均>0.05)。结论腮腺显像可灵敏地监测甲状腺癌手术患者131I治疗后腮腺功能的变化。
Objective To study the uptake and excretion of the parotid gland by radioactive iodine (131I) after parotidectomy in patients with thyroid cancer. Methods Twenty-two patients with thyroid cancer were divided into two groups: the first treatment group (group 1) and the second treatment group (group 2). All patients underwent 131I treatment and 3 months after the treatment. Parotid imaging Radioactive uptake index (UI) and excretion index (EI) after acidic stimulation, and the function of parotid gland was analyzed. Results The UI and EI of the parotids decreased by 24.7% and 25.5%, respectively (t = 2.0265 and 2.1043, respectively, P = 0.0498 and 0.0420, respectively) in the first treatment group after 131I treatment for thyroid cancer patients. 131 I treatment After the parotid UI and EI decreased 34.4% and 39.7% (t values were 1.1204,2.1575, P values were 0.0455,0.0422, respectively); but there was no significant difference in the parotid UI and EI between the two groups after treatment (t ’(UI) = 1.2331 after treatment t (EI) = 1.0474 P values were> 0.05). Conclusion Parotid gland imaging can sensitively monitor the function of parotid glands in 131I-treated thyroid cancer patients.