论文部分内容阅读
Treatment of valve diseases is common in cardiac surgery, however, an optimal heart valve prosthesis has not yet been found.Biological heart valves show excellent hemodynamic behaviour and low risk of thromboembolic complications but are limited by tissue deterioration.Mechanical heart valves do have an extended durability, however long live anticoagulation is needed.Therefore a new generation heart valve is needed to overcome these disadvantages, showing the advantages of a healthy viable tissue valve with remodelling, regeneration and growth potential.Tissue engineering would be able to create such a heart valve with all the advantages of a regular healthy valve.