Contractability of Inclusion Bodies

• 作 者: (S)pelaPeternel;MarjanBele;VladkaGaberc-Porekar;RadovanKomel;
• 机 构: National Institute of Chemistry Hajdrihova 19, SI-1000 Ljubljana Slovenia
• 出 处: 2008中国深圳蛋白质和多肽科学大会
• 发表日期: 2008年期

　　Granulocyte Colony-Stimulating Factor (G-CSF),when produced in E.coli at lower temperature (around 25℃),forms inclusion bodies (IBs) containing large amount of correctly folded protein precursor.Such inclusion bodies have remarkably different properties in comparison to classical inclusion bodies,therefore We proposed the term "nonclassical inclusion bodies" (ncIBs).Here we would like to expose some typical new characteristics of such ncIBs.