【摘 要】
：
盛华医药在中草药中发现抗病毒有效成分，经过化学修饰，开发出具有抗HPV活性的没食子酸衍生物，在83个国家申报了专利，中国、韩国、非洲组织等多个国家和地区已经获得授权.目前，市场上尚无抗HPV的有效药物.HPV对人类造成很大威胁，长时间感染易诱生癌症，已发现宫颈癌、食道癌等15％的恶性肿瘤与HPV感染有关.葛兰素史克(GSK)与默沙东(Merck)公司投入巨资，开发出预防宫颈癌的HPV疫苗，已在美国
【出 处】
：
中国上海第七届国际新药发明科技年会
论文部分内容阅读
盛华医药在中草药中发现抗病毒有效成分，经过化学修饰，开发出具有抗HPV活性的没食子酸衍生物，在83个国家申报了专利，中国、韩国、非洲组织等多个国家和地区已经获得授权.目前，市场上尚无抗HPV的有效药物.HPV对人类造成很大威胁，长时间感染易诱生癌症，已发现宫颈癌、食道癌等15％的恶性肿瘤与HPV感染有关.葛兰素史克(GSK)与默沙东(Merck)公司投入巨资，开发出预防宫颈癌的HPV疫苗，已在美国等地上市，但仅对未感染HPV者有效.RT-PCR检测发现，其专利化合物对HPV6、11、16、18型具有完全杀灭作用.在产品使用过程中发现，慢性宫颈炎和HPV阳性的患者局部使用盛华医药产品施法迪TM抗病毒凝胶，约使用12支后HPV转阴，同时，宫颈炎、重度宫颈糜烂可痊愈.现寻求与国内外企业合作，谋求共同发展.
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