共组装靶向聚合物载药胶束抗癌研究

来源 :2015年全国高分子学术论文报告会 | 被引量 : 0次 | 上传用户：shahua001

【摘要】

：

双亲嵌段聚合物胶束作为一种药物输送体系的载体被广泛研究，其中靶向体系尤其突出。本研究以cyclic(Arg-Gly-Asp-D-Phe-Lys)c(RGDfK)作为靶向基团修饰聚乙二醇-聚己内酯嵌段聚合物(cRGD-PEO-b-PCL)，和pH 敏感的聚乙二醇修饰的抗癌药阿霉素(PEG-DOX)为骨架进行共组装形成载药胶束。

【作者】

：

杨赛娜朱飞燕张应强屈小中甘志华杨振忠

【机构】

：

中国科学院化学研究所,北京市海淀区中关村北一街2号,100190 中国科学院大学,北京市石景山区玉

【出处】

：

2015年全国高分子学术论文报告会

【发表日期】

：

2015年7期

【关键词】

：

阿霉素紫杉醇胶束共组装

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共组装靶向聚合物载药胶束抗癌研究

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