Prevalence and molecular typing of the antiseptic resistance genes qacA/B among Staphylococcus aureu

• 作 者: XiaoYuWei[1]TaoLuo[2]BeiJia;LiJunChang;XiaoQiangLi;WenXiangHuang;
• 机 构: Key Laboratory of Infectious and Parasitic Diseases in Chongqing,Infectious Disease Department,First
• 出 处: 中国药理学会第十一届全国化疗药理学术研讨会
• 发表日期: 2012年期

　　Background The qacA/B genes are found in Staphylococcus aureus and confer resistance to various antiseptics and disinfectants.Herein,the prevalence of the qacA/B genes in methicillin-resistant S.aureus(MRSA)and methicillinsensitive S.aureus(MSSA)is investigated.Molecular typing systems are used to analyse the relatedness of these qacA/B-positive strains.Methods One hundred and seventy-six strains of clinically isolated S.aureus were collected between July 2008 and June 2010.The strains carrying the qacA/B genes were characterised by pulse-field gel electrophoresis(PFGE)typing,Staphylococcus protein A(spa)typing,Panton-Valentine leucocidin(pvl)PCR detection,staphylococcal chromosomal cassette(SCC)mec typing,and antimicrobial resistance profiles.