【摘 要】
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The future of nuclear cardiology has been question in the last few years as advancing cardiac CT technology and accumulating clinical data provides signific
【机 构】
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Department of Medicine and Cardiology Macquarie University School of Advanced Medicine Australia
【出 处】
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BITs 1rd Annual World Cancer Congress of Cardiology-2009(200
论文部分内容阅读
The future of nuclear cardiology has been question in the last few years as advancing cardiac CT technology and accumulating clinical data provides significant momentum in the use of this new imaging tool.It is however to be noted that cardiac CT is principally used for assessment of first and second order coronary anatomy, and that the control of coronary blood flow to the myocardium is mainly at the level of microcirculation.Importantly, it is to be stressed that ischemia is the cause of cardiac events.While atherosclerosis is an important substrate for ischemia its anatomic presence plays only a partial etiologic role in the development ofischemia, as the latter is a complex interplay of flow and flow reserve, coronary anatomy, plague morphology and burden, oxygen supply and demand; as well as endothelial function, degree of vascular inflammation, neurohumoral factors, and intravascular coagulation status etc.Both coronary blood flow and ischemia are aspects of myocardial coronary artery function, which have been extensively studied by noninvasive nuclear cardiology imaging techniques.
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