Testicular orphan receptor 4 (TR4) is a marker for metastasis and poor prognosis in NSCLC that drive

来源 :第十七届全国临床肿瘤学大会暨2014年CSCO学术年会 | 被引量 : 0次 | 上传用户：fstjqx

【摘要】

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【作者】

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Liyi Zhang Yuanyuan Ma

【机构】

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100142 Department of Thoracic Surgery Ⅱ, Peking University Cancer Hospital & Institute

【出处】

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第十七届全国临床肿瘤学大会暨2014年CSCO学术年会

【发表日期】

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2014年11期

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Objeetive: NSCLC are particularly aggressive tumors, with high invasive properties and metastatic potential.About 40％ stage Ⅰ and 60％ stage Ⅱ NSCLC patients are dying of distant metastases within 5 years after curative tumor resection.Aberrant expression of Testicular orphan receptor 4 (TR4) has been shown to regulate biologic processes around solid tumors.However, it is not clear the role of TR4 in prognosis for non small cell lung cancer (NSCLC) patients and the development of NSCLC cells.Therefore, we aimed to explore the crucial role of TR4 in 293 cases of Ⅰ-ⅢA NSCLC.

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