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目的:腺病毒(AdV)是人类呼吸道和消化道疾病的病原体,能引起急性咽炎、婴幼儿致死性肺炎、流行性结膜炎、膀胱炎、肠炎等组织炎症以及扁桃体、腺体和淋巴组织的隐性或持续性感染。荔枝核黄酮类化合物(FLC)来源于无患子科植物荔枝(Litchi Chinensis Sonn)的成熟种子,除具有降血糖、调血脂和抗氧化作用等多种功效外,还具有抗病毒作用,已有文献报道其具有体外抗乙型肝炎病毒(HBV)、流感病毒(IFV)、呼吸道合胞病毒(RSV)、SARS病毒、单纯疱疹病毒(HSV)等多种病毒作用,但未见有对腺病毒作用的研究,为此作者进行了FLC体外抗腺病毒的研究。
Objective: Adenovirus (AdV) is the pathogen of human respiratory and gastrointestinal diseases, can cause acute pharyngitis, infantile lethal pneumonia, epidemic conjunctivitis, cystitis, enteritis and other tissue inflammation and tonsil, gland and lymphoid tissue hidden Sexual or persistent infection. Litchi flavonoids (FLC) from the mature plant Litchi Chinensis Sonn seeds, in addition to hypoglycemic, lipid-lowering and anti-oxidation and other effects, but also has antiviral effects, there have been Reported in the literature with its in vitro anti-hepatitis B virus (HBV), influenza virus (IFV), respiratory syncytial virus (RSV), SARS virus, herpes simplex virus (HSV) and other viruses, but no adenovirus The role of the study, for which the authors conducted a study of FLC anti-adenovirus in vitro.