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Medicine is crucial for orchestrating development of human beings,various drugs are our close friends,help us struggle with environmental and autologous dangers.Whereas,drugs become another threaten for our health.Clinic irrational Drug-usage which is account for various reasons in China,results in serious consequences.For example,multiple drug-resistant bacteria have appeared because of antibiotic abuse.In light of current state,a system: Drugs Rational Usage Guidline System (DRUGS)was developed to improve the phenomenon of unreasonable medication.DRUGS is the first medication standard for clinical common diseases in China.It is expected to provide an available tool for improvement of rational drug usage.