基于碳量子点聚集分散机制实现对磷酸酶活性定量检测

来源 :2016全国生命分析化学学术大会 | 被引量 : 0次 | 上传用户:feixiang20090911
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  碳量子点作为一种新型的荧光纳米材料,具有发光效率高、水溶性好和生物兼容性好的优点,因此被广泛用于化学和生物传感器的构建。我们课题组利用铈离子、铜离子和镍离子对表面富含羧基的碳量子点的良好配位能力实现了对碳量子点的有效聚集,通过碳量子点的聚集实现了其荧光信号的关闭;通过引入对金属离子具有更强配位能力的竞争物种,比如焦磷酸根离子和三磷酸腺苷等,可以有效地将碳量子点聚集体重新分散,从而实现对其荧光的打开。基于以上聚集分散机制构建了基于碳量子点的荧光纳米开关。
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