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  5. Preparation and evaluation of the Berberine Hydrochloride microemulsion

Preparation and evaluation of the Berberine Hydrochloride microemulsion

来源 :2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 | 被引量 : 0次 | 上传用户：idalu
【摘 要】
：
A O/W microemulsion system of berberine hydrochloride(BBR) was prepared and evaluated for its solubilization capacity and oral bioavailability.Based on a solubility study and pseudo ternary phase diag
【作 者】
：
Xiuling Lu Xiongbin Hu Siyan Mo Dehua Liao Tiantian Tang Daxiong Xiang 
【机 构】
：
Department of Pharmacy of the Second Xiangya Hospital,Hunan Changsha 410011;Institute of clinical ph
【出 处】
：
2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会
【发表日期】
：
2014年8期
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　　A O/W microemulsion system of berberine hydrochloride(BBR) was prepared and evaluated for its solubilization capacity and oral bioavailability.Based on a solubility study and pseudo ternary phase diagrams,berberine hydrochloride microemulsions (BBR ME) of about 18.98 nm in mean diameter ware formulated with improved solubility towards the BBR raw drug with poor water solubility and membrane permeability.
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