Tautomerization-dependent Recognition and Excision of Oxidation Damage in Base-excision DNA Repair

来源 :中国化学会第十届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：forlichking

【摘要】

：

NEIL1 is a DNA repair glycosylase guarding the mammalian genome against oxidized DNA bases.As the first enzymes in the base-excision repair pathway,glycosylases must recognize the cognate substrates a

【作者】

：

Chenxu Zhu Lining Lu Jun Zhang Zongwei Yue Jinghui Song Shuai Zong Menghao Liu Olivia Stovicek Yiqin Gao Chengqi Yi

【机构】

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State Key Laboratory of Protein and Plant Gene Research,School of Life Sciences,Peking University,Be

【出处】

：

中国化学会第十届全国化学生物学学术会议

【发表日期】

：

2017年10期

【关键词】

：

Base excision repair substrate recognition enzyme catalysis DNA glycosylase QM/M

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Tautomerization-dependent Recognition and Excision of Oxidation Damage in Base-excision DNA Repair

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