Silica Nanoparticles Induce the Apoptosis and Necroptosis of Spermatogenic Cells by RIPK1 Signal Pat

• 作 者: LihuaRen;JinZhang;YangZou;LianshuangZhang;JialiuWei;ZhiweiSun;ZhixiongShi;CaixiaGuoYanboLi;XianqingZhou;
• 机 构: Department of Toxicology and Hygienic Chemistry, School of Public Health,Capital Medical University,
• 出 处: 首都医科大学第三届研究生学术论坛
• 发表日期: 2015年期

　　Although it is known that nanoparticles is of reproductive toxicity, it is not clear about its mechanism.To investigate the toxicity mechanism of silica nanoparticles (SiNPs) on spermatogenic cells, sixty C57 male mice were randomly average divided into three groups □the control group, the saline control group, the SiNPs group□with two observed time point(45 days, 75 days).