Molecular Breast Imaging, What will the Future Bring

• 作 者: Khalkhali Iraj
• 机 构: DavidGeffenSchoolofMedicineatUCLABreastDiagnosticCenterandOutpatientRadiologyServicesHarbor-UCLAMedi
• 出 处: (BITs 3rd Annual World Cancer Congress-2010, Breast Cancer C
• 发表日期: 2010年4期

　　Despite its overall success, mammography has had its limitations.For the past decade, however, the rate of lesion detection by mammography has been significantly improved.This is mainly due to use of dedicated mammography units, film processors, efficiently matched-screen combinations, improved education of radiologistsand mammography techniques, tighter regulations by the Food and Drug Administration, and the American College of Radiology.Finally,in the last decade increasing use of full field digital mammography has played a major role in early breast cancer detection.In the U.S.trials, mammography has had specificities and positive predictive value for the detection of breast cancer on the order of 20% to 30%.Thus, only 1 of every 4 to 6 "mammography suspicious" lesions biopsies will prove to be malignant.The majority of biopsies, therefore, maybe considered "unnecessary procedures".In European trials, the positive predictive value of mammography for breast cancer detection is significantly higher than in U.S.trials.