High Resolution NMR Spectra in Inhomogeneous and Unstable Fields via Intermolecular Multiple-quantum

来源 :第一届海峡两岸磁共振学术会议 | 被引量 : 0次 | 上传用户:qdchengr
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  For proton NMR,homogeneity of the magnetic field in order of 10-8 is often required to obtain chemical shift and scalar coupling information for a liquid sample.However,there are many circumstances where the spatial and temporal homogeneity of the magnetic field is degraded.To achieve high-resolution spectra in inhomogeneous field,Warren and co-workers first proposed HOMOGENIZED sequence via intermolecular multiple-quantum coherences (iMQCs).[1] We proposed IDEAL (Intermolecular Dipolar-interaction Enhanced All Lines)[2] and SEL-HOMOGENIZED (SELective HOMOGENIZED) sequences[3] with selective radio-frequency (RF) pulses to simplify NMR spectra in inhomogeneous fields.A 1.5 times magnification of scalar coupling constants from the IDEAL sequence allows more accurate measurement of J coupling.Recently,we designed an intermolecular zero-quantum coherence (iZQC) sequence with a double-quantum filter,named DQF-HOMOGENIZED,to suppress both the conventional single-quantum coherence (SQC) and iZQC signals of solvent.
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