Phosphorylation Networks in Humans Revealed by Protein Microarray Analysis

• 作 者: HengZhu;
• 机 构: Johns Hopking University School of Medicine
• 出 处: 第二届中国生物芯片应用大会
• 发表日期: 2009年期

　　Protein phosphorylation is one of the most important posttranslational modifications that regulate different cellular processes.However, a comprehensive understanding of the phosphorylation networks and pathways is still lacking in higher eukaryotes.Here we used a combined bioinformatics and protein microarray-based strategy to determine the kinase-substrate interactions in humans.