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Background: Mouse models are widely used in research of cardiac pathologies.To enable cardiac imaging in mice without having to invest in expensive dedicated equipment, we adapted a clinical 1.ST magnetic resonance imaging (MRI) scanner for a ischemia/reperfusion model in mice.We aimed to determine correlation between infarct size evaluated by late gadolinium enhancement (LGE) in comparison with histological methods.Additionaly we investigated correlation of functional parameters measured by single slice cine MRI with the standard echocardiography in mice.Methods: Mice subjected to ischemia/reperfusion procedure were randomized into groups of 0, 30 and 60 min of ischemia.LGE facilitated the determination of in vivo infarct sizes which were compared to histological infarct sizes.In addition, fractional shortening (FS) measured with echocardiography was matched to fractional area change (FAC) assessed with cine MRI.Results: There was good correlation between infarct size measured by adapted PSIR sequence and histological infarct size (r=0.869 p<0.001).Also, functional parameters acquired from CINE imaging (FAC) and echocardiography (FS) showed good correlation (r=0.807, p<0.001).Conclusion: Here we demonstrate that cardiac MRI in mice using clinical 1.5T MRI scanners enables quantification of in vivo infarction areas as well as assessment of cardiac functional parameters in an ischemia/reperfusion mouse model.