• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Oculohypotensive effect of topical losartan potassium in ocular normotensive and steroid-induced ocu

Oculohypotensive effect of topical losartan potassium in ocular normotensive and steroid-induced ocu

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：bkguo2008
【摘 要】
：
Aim: Systemically administered angiotensin Ⅱ receptor blocker, losartan, has been shown to reduce intraocular pressure (IOP) in animals and human.The aim of the current study was to compare the ocular
【作 者】
：
Tajul Atiqah ZAULKAFALI Siti Nur Laili MOHAMED RaJa Nor Intan YASSIN Anna KRASILNIKOVA Renu AGARWAL Puneet AGARWAL Nafeeza ISMAIL 
【机 构】
：
Faculty of medicine, UniversitiTeknologi of MARK Sungai Buloh Campus, 47000 Sungai Buloh,Selangor, M
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
losartan intraocular pressure steroid-induced ocular hypertension 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Aim: Systemically administered angiotensin Ⅱ receptor blocker, losartan, has been shown to reduce intraocular pressure (IOP) in animals and human.The aim of the current study was to compare the ocular hypotensive effect of topical losartan in normotensive and steroid-induced ocular hypertensive rats.Methods: Ocular hypertension was developed in normotensive Sprague Dawley rats by topical instillation of dexamethasone 0.1％, 2 times daily for 36 d.The rats that developed more than 25％ rise in IOP were considered ocular hypertensive.
其他文献
Evaluation of the anticataract effects of magnesium taurate in vitro
Aim: Magnesium (Mg) is important in the lens epithelial Na-K-ATPase activity, which in turn maintains a low intracellular sodium and calcium and a high potassium.Mg also plays a role in preserving ant
会议
cataractin vitro studyMg tauratemagnesiumcalciumglutathionecatalasesupero
Effects of Liuwei Dihuang decoction and its compatible prescriptions on urine metabolites of cortiso
Aim: To investigate the effects of Liuwei Dihuang decoction (LW) and its San-bu (three tonics) and San-xie (three eliminators) components on urine metabolites of kidney-Yin deficiency mouse model indu
会议
Liuwei Dihuang decoctionKidney-Yin deficiency mouse modelMetabolite
Effects and the mechanism of lignans from Eucommia ulmoides on rat mesangial cell proliferation indu
Aim: To study the effects of lignans from Eucommia ulmoides on the proliferation in rat mesangial cell induced by Ang Ⅱ, providing theoretical basis for the application of lignans from Eucommia ulmoid
会议
Ang Ⅱcelluar proliferationcell cyclecell apoptosislignans from Eucommia ulmo
Protective effect of FLC against LPS/D-GaIN-induced liver injury in mice
Aim: The aim of the the present study was to investigate the effects of FLC, a plantderived compound, on the acute liver injury in mice induced by LPS/D-GalN.Methods: A mixture of LPS/D-GalN was admin
会议
FLCLPS/D-GalNsurvival rateASTALT
Endothelium-dependent vasorelaxation induced by an ethanol extract of Rubus chingii Hu (Rosaceae)
Aim: Rubus chingii Hu (RC) is an important traditional Chinese medicine.It has been shown to have antioxidant and antiinflammatory effects.The present study was performed to evaluate the vascular effe
会议
Rubus chingii HuAkteNOSnitric oxideCa2+
Effects of total saponins of chaenomeles speciosa on the number and degranulation ratio of mast cell
Aim: To observe the effects of total saponins of Chaenomeles speciosa (TSCS) on synovial pathology,synovial mast cell degranulation and tryptase expression and to investigate the relationship between
会议
total saponins of Chaenomeles speciosaadjuvant arthritismast cellsdegranulati
Research of pharmacodynamics and mechanism of ChaiQingxiaopi capsule on hyperplasia of mammary gland
Aim: To study the therapentic effect of ChaiQingxiaopi capsule (CQC) on the hyperplasia of mammary glands (HMG) in rats and analyze the possible mechanism in treating HMG.Methods: (1) Seventy rats wer
会议
ChaiQingxiaopi capsule (CQC)hyperplasia of mammary glands (HMG)pharmacodynamic
Effect of baicalin on phosphorylation of TBC1D1 in skeletal muscle
Aim: Baicalin can improve insulin sensitivity, but little is known about the underlying mechanism.Whether baicalin prevent abnormal glucose tolerance in high fat diet mice.whether baicalm regulate ins
会议
baicalinglucose toleranceskeletal muscleAktTBC1D1
Over-expression of SIRT1 regulates differentiation of human visceral adipose-derived stem cells
Aim: Human adipose tissue-derived stem cells (hADSCs) have ability to selfrenew and differentiate into multiple tissues.Recent studies reveal that NADdependent protein deacetylase SIRT1 is required fo
会议
SIRT1human adipose tissue-derived stem ceilswhite fatbrown adipose tissue
Methyl palmitate inhibits cell proliferation but promotes cell migration in human mesenchymal stem c
Aim: To investigate the effects of the methyl palmitate (PAME) on the proliferation and migration of human bone marrow mesenchymal stem cells (hMSCs).Methods: The hMSCs were incubated with various con
会议
mesenchymal stem cellsmethyl palmitate (PAME)proliferationmigration