A combined genome-wide DNA methylation and transcription analysis identified genes related with path

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：amaozh

【摘要】

：

　　Objectives: Systemic sclerosis (SSc) is an autoimmune disease with unknown etiology.Studies have revealed epigenetic modification can contribute to suscepti

【作者】

：

HonglinZhu[1]HuiLuo[1]TaoChen[2]ShengxiLiu[2]QuanzhenLi[2]XiaoxiaZuo[1]

【机构】

：

Department of Rheumatology,Xiangya Hospital,Central South University,87 Xiangya Road,Changsha,Hunan

【出处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Objectives: Systemic sclerosis (SSc) is an autoimmune disease with unknown etiology.Studies have revealed epigenetic modification can contribute to susceptibility and pathogenic process in systemic autoimmune diseases by regulating gene activation or silencing.

其他文献

PMNs凋亡异常与SLE的相关性研究

　　背景、目的：大量研究发现细胞凋亡可能参与炎症反应，与一些自身免疫性疾病的发生密切相关。越来越多的研究证据表明SLE患者存在细胞凋亡紊乱，但SLE与PMNs凋亡的相关性以及PM

会议

PMNs细胞凋亡SLE自身免疫性疾病炎症反应病理机制证据患者

Aloperine attenuate mice symptoms from colitis by regulating PI3K/AKT/mTOR signaling pathway and Fox

　　Aloperine has been recognized with the potential capacity to treat inflammatory and allergic diseases as well as colitis.Treg plays a key role in IBD.

会议

Clinical and serological characteristics of primary Sj(o)gren's syndrome with IgG4-positive pla

　　Objective: The purpose of this study was to investigate the clinical and serological characteristics of Primary Sjgren's syndrome (pSS) patients with differ

会议

Type 1 Regulatory T Cell Differentiation Induced by IL-12 Is Impaired in Patients with Sj(o)gren'

　　Background and Objectives: Type 1 regulatory T cell (Tr1) is an inducible subset of regulatory T cells, characterized by the capability to secrete immunosup

会议

TLR4通路诱导上皮间质转化在原发性胆汁性肝硬化中的作用研究

　　背景：原发性胆汁性肝硬化(PBC)是以肝内胆管上皮细胞损伤为主要特征的慢性胆汁淤积性自身免疫性肝病，病因和发病机制尚不完全清楚。目的：探讨LPS-TLR4通路与上皮间质转化在

会议

TLR4通路诱导上皮间质原发性胆汁性肝硬化自身免疫性肝病上皮细胞损伤作用机制

A combined genome-wide transcription analysis and DNA methylation identified genes related with path

　　Objectives: Lupus nephritis (LN) is one of the most devastating complications and a main cause of morbidity and mortality in systemic lupus erythematosus(SL

会议

High throughput sequencing uncovers a specific pattern of γδT cells in patients with SAPHO syndrome

　　Objective: The etiology of SAPHO (acronym for synovitis, acne, pustulosis, hyperostosis and osteitis) syndrome may involves infection and immune disorder.

会议

特异性检测人可溶性B7-H2蛋白ELISA试剂盒的研制及应用

　　研究目的：T细胞的有效活化和功能介导需要共刺激信号的参与.B7-H2是重要的正性共刺激分子，可以与其受体ICOS结合促进T细胞的增殖和细胞因子的分泌.在移植免疫、感染免疫、

会议

特异性检测人可溶性蛋白ELISA试剂盒自身免疫性疾病细胞的增殖免疫调节作用高灵敏度检测

雌激素受体在痛风病人中表达差异的研究

　　目的：痛风性关节炎(Gout,GA)是一种人类最古老,最疼痛的关节炎之一,在40岁以上男性和绝经期女性中最为常见,是一种由于单尿酸钠结晶(monocodium urate,MSU)从超饱和状态沉

会议

雌激素受体痛风性关节炎病人绝经期女性滑膜组织饱和状态炎症性尿酸钠

Soluble PD-1 Aggravates Progression of Collagen-Induced Arthritis Through Th1 and Th17 pathways

　　Intoduction: The programmed death 1 (PD-1) protein is a critical regulator of T-cell activation and is also an important therapeutic target for autoimmune d

会议

A combined genome-wide DNA methylation and transcription analysis identified genes related with path

其他学术论文