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I do respect to my patients for their cooperation during the process ofthe study.Background/Aims: Hepatitis C is an progressing global health problem.The expense of the exciting regimen for treatment is not available for many patients.Herbal medicine have been used as complementary therapy in the treatment of liver diseases for a long time.In the current study the herbal medicine used in treatment of HCV are Milk Thistle,Phyllanthus,Garlic,Cinnamon,parsley,Black seed and AKHY-J-25 (mixture of herbs).The aims is to assess the efficacy of that complementary therapy in treating chronic hepatitis C.