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In recent years, there has been growing interest in the use of magnetic iron oxide nanoparticles as drug carrier, delivery vehicle, hyperthermia agent or imaging label [1].To fulfill these applications, magnetic labeling of cells via endocytosis is needed.Magnetic nanoparticles can be endocytosed through specific or non-specific interactions between magnetic nanoparticles and cells.An extent of nanoparticle internalization into cells could vary depending on versatility of cellular phenotypes [2].According to these heterogeneities some cells heavily labeled and other cells only contained trace amount of magnetic nanoparticles.Besides cytotoxicity, the impacts of magnetic labeling on cell function such as inhibitory effect of cell motility or cell differentiation in a dose-dependent manner have been reported [3].Due to the importance of cellular perturbations by the magnetic cellular contents,an efficient cell separation based on uptake capacity is still required.In a recent study, Robert et al.demonstrated that cells could be sorted by their endocytotic capacity in a magnetophoretic device with rectangle geometry [2].However, cells in a conventional rectangular microchannel were exposed to the same strength of magnetic field, and thus it is difficult to separate cells which are loaded with a little amount of magnetic nanoparticles.