【摘 要】
:
To investigate whether phosphorylation level of cAMP-responsive element binding protein (p-CREB) and allopregnanolone content in hippocampus could be the bi
【机 构】
:
Civil Aviation Medical Center of CAAC, Beijing 100025, China
【出 处】
:
The 6th Asia Pacific Congress of Aerospace Medicine in Conju
论文部分内容阅读
To investigate whether phosphorylation level of cAMP-responsive element binding protein (p-CREB) and allopregnanolone content in hippocampus could be the biomarkers for the effect of acute alcohol administration on neurobehavioral function.Alcohol was administered to rats by intragastric lavage with doses of 1,2 and 3 g/kg.Two h later,Morris Water Maze performance was applied to evaluate neurobehavioral function,and p-CREB in rat hippocampus was determined by Western Blotting,while allopregnanolone content was measured by HPLC-ESI-MS/MS.Neurobehavioral function,p-CREB level and allopregnanolone content were determined at 0.5,1,2,4 and 8 hour after administration with alcohol 3g/kg.
其他文献
目的 我国医疗器械产业发展至今已颇具规模,市场规模增长率一直保持在20%左右.本研究分析鞍山市立山区各级公立医疗机构现有医疗器械配置情况,特别是数字化X线摄影系统(digita
【摘 要】目前,我国高等学校中大多数专业没有开设专业导论课程,这种情况常常导致许多学生在大学学习过程中表现为只知课本知识点,不见专业全貌的现象,其主要原因是一些高校对专业导论课的重要作用认识不到位以及相应的制度政策引导不够。开设专业导论课对帮助大学生尽早了解所学专业性质、培养专业兴趣、掌握专业学习方法、规划自身发展具有重要的导航作用。高等学校应该在更新教育观念、加强教学管理、集中优势师资、编写特色
To study modafinil-induced blood oxygenation level-dependent (BOLD) regional brain activity during working memory after 36 hours total sleep deprivation (SD
9月2日,北京最大的古旧家具市场——高碑店古典家具民俗园落成。高碑店作为中国民间古旧家具的集散地,素有“古旧家具之乡”的美誉。早在20世纪90年代,高碑店乡就自发形成了
正常的课堂教学,教师不能一讲到底,总要辅之以必要的课堂提问和练习等等.课堂提问是教师在教学中最常用的教学方法,是阅读教学一项重要基本功.提问用得恰当,就有助于教学质量